Events
- 1440: Eton College founded by Henry VI.
- 1441: Jan van Eyck, Flemish painter, dies.
- 1441: Portuguese navigators cruise West Africa and reestablish the European slave trade with a shipment of African slaves sent directly from Africa to Portugal.
- 1442: Leonardo Bruni defines Middle Ages and Modern times.
- 1445 – Printing press developed in Europe
Art
- Anonymous – The Triumph of Death (c.1446)
- Hans Bornemann – Heiligentaler Altar (Altarpiece of St. Nicholas) (after 1444)
- Petrus Christus
- Lamentation (Pietà) (c.1444)
- Portrait of a Carthusian (1446)
- Niccolò Antonio Colantonio – Delivery of the Franciscan Rule (c.1445)
- Lluís Dalmau
- Virgin of the Consellers (1443-1445)
- Andrea del Castagno – Frescoes
- The Last Supper (1445-1450)
- Piero della Francesca
- The Baptism of Christ (completed c.1448-1450)
- Barthélemy d’Eyck (attributed) – Aix Annunciation (1443-1445)
- Giovanni di Paolo
- Guelfi Altarpiece (1445)
- Illuminations of Dante’s Paradiso (c.1444-1450)
- Jean Fouquet – Portrait of Pope Eugene IV (before 1447)
- Jost Haller − Tempelhof Altarpiece (ca. 1445)
- Filippo Lippi
- Annunciation (completed c.1443-1450)
- Annunciation (completed c.1445-1450)
- The Annunciation with two Kneeling Donors (1440-1445)
- Coronation of the Virgin (1441-1447)
- Marsuppini Coronation (after 1444)
- Martelli Annunciation (c.1440)
- Andrea Mantegna – Saint Jerome in the Wilderness (c.1448–1451)
- Pisanello
- Portrait of a Princess of the House of Este (c.1435-1449)
- Cecilia Gonzaga commemorative medal (1447)
- Stefano di Giovanni (Sassetta) – The Meeting of St. Anthony and St. Paul (c.1440)
- Tenshō Shūbun – Reading in a Bamboo Grove
- Paolo Uccello
- The Battle of San Romano (triptych, c.1435-1455)
- Rogier van der Weyden
- The Descent from the Cross (c.1435)
- The Exhumation of Saint Hubert (c.1437-1440)
- Beaune Altarpiece (c.1445-1450)
- Miraflores Altarpiece (c.1442-1445)
- Portrait of Isabella of Portugal (c.1445-1450)
- Saint Luke Drawing the Virgin (“Self-portrait as Saint Luke”) (c.1435-1440)
- Seven Sacraments Altarpiece (1445-1450)
- Frontispiece of the Chroniques de Hainaut (1447)
- Jan van Eyck
- Annunciation (c.1440)
- Portrait of Christ (“Vera Icon”) (c.1440)
- Saint Jerome in His Study (1442)
- Domenico Veneziano
- Santa Lucia de’ Magnoli Altarpiece (c.1445-1447)
- Konrad Witz
- Saint Madeleine and Saint Catherine (c. 1440)
- The Miraculous Draft of Fishes (1444)
